DSpace width= university logo mark
Japanese | English 

KURA > C. 医薬保健学域・研究域/医・薬学部/医学系研究科 > c10. 学術雑誌掲載論文(医・保健) > 1. 査読済論文(医学・保健) >


ファイル 記述 サイズフォーマット
ME-PR-NAKANUMA-Y-33.pdf786.46 kBAdobe PDF
タイトル: Long-term histologic follow-up study of alcoholic liver disease.
著者: Motoo, Yoshiharu link image
Wakatsuki, Toshinosuke
Nakanuma, Yasuni link image
元雄, 良治
中沼, 安二
発行日: 1992年 1月
出版社(者): 日本内科学会 = Japanese Society of Internal Medicine
雑誌名: Internal medicine (Tokyo, Japan)
ISSN: 0918-2918
巻: 31
号: 1
開始ページ: 33
終了ページ: 38
キーワード: alcoholic hepatitis
fatty liver
hepatic fibrosis
chronic hepatitis
liver cirrhosis
repeated liver biopsies
抄録: Forty Japanese patients with alcoholic liver disease (nonspecific change, 9; fatty liver, 5; hepatic fibrosis, 4; chronic hepatitis, 12; alcoholic hepatitis, 5; liver cirrhosis, 5) were followed for 3-17 yr (average 8 yr) with repeated liver biopsies (2-5 times; average 2.5 times) at intervals of more than 3 yr. All of the patients continued to consume alcohol during this observation period. Five out of 12 patients with chronic hepatitis and 2 of 5 patients with alcoholic hepatitis eventually progressed to cirrhosis, while none of the 4 patients with hepatic fibrosis became cirrhotic. Anti-hepatitis C virus antibody was positive in 2 patients with liver cirrhosis among 12 patients whose sera were available. Two patients with cirrhosis died of hepatic failure and one patient died of hepatocellular carcinoma. These data suggest that the long-term prognosis of alcoholic liver disease is not necessarily poor, but patients with chronic hepatitis or alcoholic hepatitis can be at risk of progression to cirrhosis.
DOI: 10.2169/internalmedicine.31.33
URI: http://hdl.handle.net/2297/16754
関連URI: http://dx.doi.org/10.2169/internalmedicine.31.33
資料種別: Journal Article
権利関係: Copyright© The Japanese Society of Internal Medicine
版表示: publisher
出現コレクション:1. 査読済論文(医学・保健)

このアイテムを引用あるいはリンクする場合は次の識別子を使用してください。 http://hdl.handle.net/2297/16754



Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - ご意見をお寄せください