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タイトル: Assessment by thallium-201 of hindlimb muscle blood flow in rats during recovery after hindlimb unloading
著者: Inaoka, Pleiades Tiharu link image link image
Amano, Ryohei link image
Tanaka, Shoji link image link image
Tachino, Katsuhiko link image
稲岡, Pleiades 千春
天野, 良平
田中, 正二
立野, 勝彦
発行日: 2009年 7月
出版社(者): Society of Physical Therapy Science = 理学療法科学会
雑誌名: Journal of Physical Therapy Science
ISSN: 0915-5287
巻: 21
号: 2
開始ページ: 163
終了ページ: 167
キーワード: Blood flow
Hindlimb reloading
Thallium-201
抄録: [Purpose] We aimed to evaluate the muscle blood perfusion by the uptake of the radioisotope thallium-201 (201Tl) in 5 hindlimb muscles, the soleus (Sol), plantaris (Pla), gastrocnemius (Gas), extensor digitorum longus (EDL), and tibialis anterior (TA). [Subjects] The subjects were 36 male Wistar rats. [Methods] 201Tl uptake rates were calculated by spectrometry and visualized by autoradiography (ARG) in hindlimb unloading (U) and reloading (R) rats. [Results] The Sol 201Tl uptake rates were significantly lower in U groups (p<0.01) than in the control group. Meanwhile the reloading day-4 group had higher values in Sol than the control (p<0.01). In U groups, the EDL and TA uptake rates were higher than in the other 3 muscles (Sol, Pla, and Gas). [Conclusion] We concluded that during 21 days of hindlimb unloading and subsequent recovery by reloading, blood capillary perfusion assessed by 201Tl in hindlimb muscles changes in rats. The results confirm the utility of 201Tl in quantitative and qualitative evaluation of skeletal muscle activity and blood perfusion, which has applications in rehabilitation and sports science.
DOI: 10.1589/jpts.21.163
URI: http://hdl.handle.net/2297/19413
関連URI: http://www.jstage.jst.go.jp/article/jpts/21/2/21_163/_article
資料種別: Journal Article
権利関係: Copyright (c) 2009 by the Society of Physical Therapy Science
版表示: publisher
出現コレクション:1. 査読済論文(医学・保健)

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