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タイトル: The Effect of Susceptibility of Gadolinium Contrast Media on Diffusion-weighted Imaging and the Apparent Diffusion Coefficient
著者: Ogura, Akio
Hayakawa, Katsumi
Miyati, Tosiaki link image link image
Maeda, Fumie
小倉, 明夫
宮地, 利明
発行日: 2008年 7月
出版社(者): Association of University Radiologists / Elsevier Science B.V.
雑誌名: Academic Radiology
ISSN: 1076-6332
巻: 15
号: 7
開始ページ: 867
終了ページ: 872
キーワード: apparent diffusion coefficient
Diffusion-weighted image
gadolinium contrast medium
susceptibility
抄録: Rationale and Objectives: The development of parallel magnetic resonance imaging has resulted in the frequent use of diffusion-weighted imaging (DWI) in clinical medicine, which usually involves the use of contrast medium. However, gadolinium (Gd) contrast medium may have some effect on DWI and the apparent diffusion coefficient (ADC). The present study was performed to determine whether the magnetic susceptibility of contrast medium alters the DWI signal and the value of ADC in some imaging techniques. Materials and Methods: Nonfat suppression DWI, short-time inversion recovery (STIR) combination, and chemical shift selective (CHESS) combination DWI were performed to examine 10 phantoms with gadolinium-meglumine gadopentetate (Gd-DTPA) dissolved at concentrations from 0.0005 to 0.1 mmol in physiologic saline as a contrast medium. The average pixel value and ADC of each method were determined. Results: ADC showed no differences between before and after treatment with contrast medium for all imaging techniques with Gd considered distributed over the whole tumor. The signal intensity did not change on nonfat suppression or CHESS combination DWI, but deteriorated on STIR. Conclusions: ADC was not influenced by the magnetic susceptibility of contrast medium. In addition, it was suggested that the ability of tumor detection may be reduced if STIR is used as fat suppression. © 2008 AUR.
DOI: 10.1016/j.acra.2007.12.020
URI: http://hdl.handle.net/2297/19575
資料種別: Journal Article
版表示: author
出現コレクション:1. 査読済論文(医学・保健)

このアイテムを引用あるいはリンクする場合は次の識別子を使用してください。 http://hdl.handle.net/2297/19575

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