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タイトル: MDCT findings of extrapancreatic nerve plexus invasion by pancreas head carcinoma: correlation with en bloc pathological specimens and diagnostic accuracy
著者: Mochizuki, Kentaro
Gabata, Toshifumi link image link image
Kozaka, Kazuto link image link image
Hattori, Yuki
Zen, Yoh
Kitagawa, Hirohisa link image
Kayahara, Masato
Ohta, Tetsuo link image link image
Matsui, Osamu link image
望月, 健太郎
蒲田, 敏文
小坂, 一斗
全, 陽
北川, 裕久
萱原, 正都
太田, 哲生
松井, 修
発行日: 2010年 7月
出版社(者): Springer Verlag (Germany)
雑誌名: European Radiology
ISSN: 0938-7994
巻: 20
号: 7
開始ページ: 1757
終了ページ: 1767
キーワード: Extrapancreatic nerve plexus
Multi-detector row CT
Nerve plexus invasion
Neural invasion
Pancreatic cancer
抄録: Objective: To elucidate the multi-detector row computed tomography (MDCT) findings of extrapancreatic nerve plexus (PLX) invasion by pancreas head carcinoma (PhC) by "point-by-point" correlation with en bloc pathological specimens and to assess their diagnostic accuracy. Methods: Each pathological section of PhC and adjusted double oblique multiplanar reconstruction MDCT images were correlated in 554 sections from 37 patients. The diagnostic accuracy of the MDCT patterns derived was assessed by blind reading. Results: PLX invasion with fibrosis showed mass or strand shape (85.6%) or coarse reticula (13.3%). The CT findings were divided into fine reticular and linear, coarse reticular, mass and strand, and nodular patterns. PLX invasion was revealed pathologically in 92% of the regions of investigation showing the mass and strand pattern and 63% of the coarse reticular pattern (all continuous with PhC), and they were highly suggestive of PLX invasion by PhC on MDCT images (p < 0.001). Sensitivity, specificity, accuracy, and positive and negative predictive values of these MDCT findings in the diagnosis of PLX invasion were 100% (25/25), 83.3% (10/12), 94.6% (35/37), 92.6% (25/27) and 100% (10/10), respectively. Conclusion: The mass and strand pattern and the coarse reticular pattern continuous with PhC on MDCT images were highly suggestive of PLX invasion by PhC. © 2010 European Society of Radiology.
DOI: 10.1007/s00330-010-1727-5
URI: http://hdl.handle.net/2297/22577
資料種別: Journal Article
版表示: author
出現コレクション:1. 査読済論文(医学・保健)

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