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タイトル: Medical procedures and risk for sporadic creutzfeldt-jakob disease, Japan, 1999-2008
著者: Hamaguchi, Tsuyoshi link image link image
Noguchi-Shinohara, Moeko
Nozaki, Ichiro
Nakamura, Yosikazu
Sato, Takeshi
Kitamoto, Tetsuyuki
Mizusawa, Hidehiro
Yamada, Masahito link image link image
濵口, 毅
篠原, もえ子
山田, 正仁
発行日: 2009年 2月
出版社(者): National Center for Infectious Diseases
雑誌名: Emerging Infectious Diseases
ISSN: 1080-6040
巻: 15
号: 2
開始ページ: 265
終了ページ: 271
抄録: To elucidate the association between medical procedures and sporadic Creutzfeldt-Jakob disease (sCJD), we analyzed medical procedures (any surgical procedure, neu- rosurgery, ophthalmic surgery, and blood transfusion) for patients registered by the CJD Surveillance Committee in Japan during 1999-2008. We conducted an age-stratified case-control study with 753 sCJD patients and 210 controls and a study of patients who underwent neurosurgical or ophthalmic surgical procedures at the same hospital. Although the control group was relatively small, no evidence was found that prion disease was transmitted through the investigated medical procedures before onset of sCJD. After onset of sCJD, 4.5% of the sCJD patients underwent operations, including neurosurgical for 0.8% and ophthalmic for 1.9%; no special precautions against transmission of prion diseases were taken. Fortunately, we have not identified patients with prion disease attributed to these operations. Our findings indicate that surgical procedures or blood transfusion had little effect on the incidence of sCJD.
DOI: 10.3201/eid1502.080749
URI: http://hdl.handle.net/2297/24042
資料種別: Journal Article
版表示: publisher
出現コレクション:1. 査読済論文(医学・保健)

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