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タイトル: The effect of L-ornithine hydrochloride ingestion on performance during incremental exhaustive ergometer bicycle exercise and ammonia metabolism during and after exercise
著者: Demura, Shinichi link image
Yamada, Takayoshi
Yamaji, Shunsuke
Komatsu, Miho
Morishita, Koji
出村, 愼一
発行日: 2010年10月
出版社(者): Nature Publishing Group
雑誌名: European Journal of Clinical Nutrition
ISSN: 0954-3007
巻: 64
号: 10
開始ページ: 1166
終了ページ: 1171
キーワード: aerobic exercise
ammonia metabolism
fatigue recovery
L-ornithine hydrochloride
抄録: Objectives:L-ornithine has an important role in ammonia metabolism via the urea cycle. This study aimed to examine the effect of L-ornithine hydrochloride ingestion on performance during incremental exhaustive ergometer bicycle exercise and ammonia metabolism during and after exercise.Subjects/Methods:In all, 14 healthy young adults (age: 22.2±1.0 years, height: 173.5±4.6 cm, body mass: 72.512.5 kg) who trained regularly conducted incremental exhaustive ergometer bicycle exercises after-ornithine hydrochloride supplementation (0.1 g/kg, body mass) and placebo conditions with a cross-over design. The exercise time (sec) of the incremental ergometer exercise, exercise intensity at exhaustion (watt), maximal oxygen uptake (ml per kg per min), maximal heart rate (beats per min) and the following serum parameters were measured before ingestion, 1 h after ingestion, just after exhaustion and 15 min after exhaustion: ornithine, ammonia, urea, lactic acid and glutamate. All indices on maximal aerobic capacity showed insignificant differences between both the conditions.Results:Plasma ammonia concentrations just after exhaustion and at 15 min after exhaustion were significantly more with ornithine ingestion than with placebo. Plasma glutamate concentrations were significantly higher after exhaustion with ornithine ingestion than with placebo.Conclusions:It was suggested that, although the ingestion of L-ornithine hydrochloride before the exercise cannot be expected to improve performance, it does increase the ability to buffer ammonia, both during and after exercise. © 2010 Macmillan Publishers Limited All rights reserved.
DOI: 10.1038/ejcn.2010.149
URI: http://hdl.handle.net/2297/25434
資料種別: Journal Article
版表示: author
出現コレクション:1-4.査読済論文(教育)

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