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タイトル: IgG4-related tubulointerstitial nephritis and hepatic inflammatory pseudotumor without hypocomplementemia
著者: Kim, Fae
Yamada, Kazunori link image link image
Inoue, Dai
Nakajima, Kenichi link image link image
Mizushima, Ichiro
Kakuchi, Yasushi
Fujii, Hiroshi link image link image
Narumi, Kenta
Matsumura, Masami link image
Umehara, Hisanori
Yamagishi, Masakazu link image link image
Kawano, Mitsuhiro link image link image
山田, 和徳
中嶋, 憲一
藤井, 博
鳴海, 兼太
松村, 正巳
山岸, 正和
川野, 充弘
発行日: 2011年
出版社(者): The Japanese Society of Internal Medicine = 日本内科学会
雑誌名: Internal Medicine
ISSN: 0918-2918
巻: 50
号: 11
開始ページ: 1239
終了ページ: 1244
キーワード: Hepatic inflammatory pseudotumor
IgG4-related tubulointerstitial nephritis
抄録: Immunoglobulin G4 (IgG4)-related tubulointerstitial nephritis (TIN) is often accompanied by autoimmune pancreatitis (AIP) or chronic sclerosing dacryoadenitis and sialoadenitis. However, IgG4-related TIN without AIP or lacrimal and/or salivary gland lesions has not been well recognized. Here, we report a case of IgG4-related TIN associated with hepatic inflammatory pseudotumor without AIP or lacrimal and/or salivary gland lesions. A 58-year-old Japanese man with epigastralgia underwent contrast-enhanced computed tomography (CT), which revealed multiple low-density lesions in both kidneys and a low density hepatic mass. Laboratory tests showed an extremely high level of serum IgG4. Percutaneous renal and hepatic biopsies showed diffuse infiltration of lymphocytes and IgG4-positive plasma cells with fibrosis in both tissues. Two months after administration of oral prednisolone, both lesions decreased in size on follow-up CT, and the serum cre-atinine level also improved. No recurrence has been detected for two years with a maintenance dose of pred-nisolone. © 2011 The Japanese Society of Internal Medicine.
DOI: 10.2169/internalmedicine.50.5102
URI: http://hdl.handle.net/2297/28339
関連URI: JST.JSTAGE/internalmedicine/50.5102
http://www.naika.or.jp/
資料種別: Journal Article
権利関係: Copyright (c) 2011 by The Japanese Society of Internal Medicine
版表示: publisher
出現コレクション:1. 査読済論文

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