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タイトル: A rapid increase in cAMP in response to 20-hydroxyecdysone in the anterior silk glands of the silkworm, Bombyx mori
著者: Elmogy, Mohamed
Terashima, Jun
Iga, Masatoshi
Iwami, Masafumi link image link image
Sakurai, Sho link image link image
岩見, 雅史
桜井, 勝
発行日: 2006年 8月
出版社(者): Zoological Society of Japan = 日本動物学会
雑誌名: Zoological science
ISSN: 0289-1824
巻: 23
号: 8
開始ページ: 715
終了ページ: 719
キーワード: Bombyx mori
Programmed cell death
Silk gland
抄録: In the anterior silk glands (ASGs) of the silkworm, Bombyx mori, intracellular cAMP increases transiently to a very high level shortly after the hemolymph ecdysteroid peak in the prepupal period. In cultured ASGs obtained on the day of gut-purge, cAMP levels were increased by 20-hydroxy-ecdysone (20E), and this increase was enhanced by an inhibitor of phosphodiesterase, but was not affected by α-amanitin, indicating the 20E action may not be mediated via gene expression. The increase in cAMP occurred within 30 seconds of exposure to a physiological concentration of 20E (1 μM), and also by ponasterone A. Our findings indicate a nongenomic action of ecdysteroids in insects, which may be an additional mechanism by which this steroid hormone induces acute responses in tissues and cells. © 2006 Zoological Society of Japan.
DOI: 10.2108/zsj.23.715
URI: http://hdl.handle.net/2297/28994
関連URI: http://www.zoology.or.jp/
資料種別: Journal Article
版表示: publisher

このアイテムを引用あるいはリンクする場合は次の識別子を使用してください。 http://hdl.handle.net/2297/28994



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