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タイトル: MR perfusion imaging by alternate slab width inversion recovery arterial spin labeling (AIRASL): a technique with higher signal-to-noise ratio at 3.0 T
著者: Fujiwara, Yasuhiro
Kimura, Hirohiko
Miyati, Tosiaki link image link image
Kabasawa, Hiroyuki
Matsuda, Tsuyoshi
Ishimori, Yoshiyuki
Yamaguchi, Isao
Adachi, Toshiki
藤原, 康博
宮地, 利明
発行日: 2012年 4月
出版社(者): Springer Verlag (Germany) / European Society for Magnetic Resonance in Medicine and Biology
雑誌名: Magnetic Resonance Materials in Physics, Biology and Medicine
ISSN: 0968-5243
巻: 25
号: 2
開始ページ: 103
終了ページ: 111
キーワード: Arterial spin labeling
High field
Magnetic resonance imaging
Perfusion
抄録: Object: To propose a new arterial spin labeling (ASL) perfusion-imaging method (alternate slab width inversion recovery ASL: AIRASL) that takes advantage of the qualities of 3.0 T. Materials and methods: AIRASL utilizes alternate slab width IR pulses for labeling blood to obtain a higher signal-to-noise ratio (SNR). Numerical simulations were used to evaluate perfusion signals. In vivo studies were performed to show the feasibility of AIRASL on five healthy subjects. We performed a statistical analysis of the differences in perfusion SNR measurements between flow-sensitive alternating inversion recovery (FAIR) and AIRASL. Results: In signal simulation, the signal obtained by AIRASL at 3.0 and 1.5 T was 1.14 and 0.85%, respectively, whereas the signal obtained by FAIR at 3.0 and 1.5 T was 0.57 and 0.47%, respectively. In an in vivo study, the SNR of FAIR (3.0 T) and FAIR (1.5 T) were 1.73 ± 0.49 and 1.02 ± 0.20, respectively, whereas the SNRs of AIRASL (3.0 T) and AIRASL (1.5 T) were 3.93 ± 1.65 and 1.34 ± 0.31, respectively. SNR in AIRASL at 3.0 T was significantly greater than that in FAIR at 3.0 T. Conclusion: The most significant potential advantage of AIRASL is its high SNR, which takes advantage of the qualities of 3.0 T. This sequence can be easily applied in the clinical setting and will enable ASL to become more relevant for clinical application. © 2012 ESMRMB.
内容記述: Article in Press エンバーゴ設定 Thesis of Fujiwara, Yasuhiro / 藤原 康博 博士学位論文(金沢大学 / 大学院医薬保健学総合研究科)
DOI: 10.1007/s10334-011-0301-8
URI: http://hdl.handle.net/2297/30568
資料種別: Journal Article
版表示: author
出現コレクション:1. 査読済論文(医学・保健)

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