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タイトル: In vitro susceptibilites to levofloxacin and various antibacterial agents of 18,639 clinical isolates obtained from 77 centers in 2004
その他のタイトル: 2004年に全国77施設から分離された臨床分離株18,639株の各種抗菌薬に対する感受性サーベイランス
著者: Yamaguchi, Keizo
Oono, Akira
Ishii, Yoshikazu
Tachida, Kazuhiro
Iwata, Morihiro
Levofloxacin-Surveillance Group
Fujita, Shin-ichi
山口, 惠三
大野, 章
石井, 良和
舘田, 一博
岩田, 守弘
レボフロキサシンサーベランスグループ
藤田, 信一
発行日: 2006年12月
出版社(者): 日本抗生物質学術協議会
雑誌名: Japanese Journal of Antibiotics
ISSN: 0368-2781
巻: 59
号: 6
開始ページ: 428
終了ページ: 451
抄録: A total of 18,639 clinical isolates in 19 species collected from 77 centers during 2004 in Japan were tested for their susceptibility to fluoroquinolones (FQs) and other selected antibiotics. The common respiratory pathogens, Streptococcus pyogenes, Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae showed a high susceptible rate against FQs. The isolation rate of beta lactamase non-producing ampicillin-resistant H. influenzae was approximately three times as large as those of western countries. Most strains of Enterobacteriaceae were also susceptible to FQs. The resistance rate of Escherichia coli against FQs has however been rapidly increasing so far as we surveyed since 1994. The FQs-resistant rate in methicillin-resistant Staphylococcus aureus (MRSA) showed approximately 90% except for 36% of sitafloxacin while FQs-resistant rate in methicillin-susceptible S. aureus (MSSA) was around 5%. The FQs-resistant rate of methicillin-resistant coagulase negative Staphylococci (MRCNS) was also higher than that of methicillin- susceptible coagulase negative Staphylococci (MSCNS), however, it was lower than that of MRSA. In Pseudomonas aeruginosa clinical isolates, 32-34% from UTI and 15-19% of from RTI was resistant to FQs. Acinetobacter spp. showed a high susceptibility to FQs. Although FQs-resistant Neisseria gonorrhoeae have not been increased in western countries, it is remarkably high in Japan. In this survey, isolates of approximately 85% was resistant to FQs.
URI: http://hdl.handle.net/2297/5612
資料種別: Journal Article
版表示: publisher
出現コレクション:1. 査読済論文

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