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タイトル: 入院患者における末梢静脈カテーテルの閉塞に対するヘパリンロックの効果
その他のタイトル: Efficacy of Heparin Lock in Maintaining Patency of Peripheral Vein Catheters in Patients
著者: 郡司, 聖子
古川, 裕之
宮下, 知治 link image link image
西村, 元一
安藤, 絹子
坂尾, 雅子
飛田, 敦子
山田, 清文
宮本, 謙一
Gunji, Kiyoko
Furukawa, Hiroyuki
Miyashita, Tomoharu
Nishimura, Genichi
Ando, Kinuko
Sakao, Masako
Tobita, Atuko
Yamada, Kiyofumi
Miyamoto, Kenichi
発行日: 2006年 2月10日
出版社(者): 日本医療薬学会
引用: 医療薬学 32(2), pp.87-95
雑誌名: 医療薬学
巻: 32
号: 2
開始ページ: 87
終了ページ: 95
キーワード: saline lock 10U mL heparin lock 100U mL heparin lock thrombus protein content peripheral vein catheter
抄録: Currently, normal saline lock or normal saline containing heparin lock are routinely used after IVH or intermittent peripheral infusion in the clinical setting. Up till now, however, there has been no evidence for the optimal concentration of heparin in the lock solution for preventing thrombus formation in peripheral vein catheters and central venous catheters. The purpose of this study was to evaluate the effectiveness of normal saline against normal saline containing 10U/mL or 100U/mL heparin for preventing blood clotting in peripheral vein catheters. Patients (N=60) in Kanazawa University Hospital were randomized to 3 groups (saline lock group, 10U/mL heparin lock group and 100U/mL heparin lock group : N=20 for each). We evaluated the rates of thrombus formation and thrombus protein content after 24 hours of lock in peripheral vein catheters. Our results indicated that when the 100U/mL heparin lock solution was used, both thrombus formation rates catheters and protein contents were significantly lower than for the other 2 groups. However, at 100U/mL, the heparin lock solution caused most pain at the insertion site, though the reason for this was not clearly known. In conclusion, as compared with the normal saline solution and the 10U/mL heparin lock solution, the 100U/mL heparin lock solution was more effective in preventing the thrombus formation in the peripheral vein catheter.
URI: http://hdl.handle.net/2297/6306
資料種別: Journal Article
版表示: publisher
出現コレクション:1. 査読済論文

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