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タイトル: Comparison of regional myocardial Technetium-99m-MIBI uptake between ECG-gated and ungated SPECT imaging
著者: Onoguchi, Masahisa link image link image
Maruno, Hirotaka
Fujinaga, Tsuyoshi
Komiyama, Nobuyuki
Takayama, Teruhiko
Murata, Hajime
小野口, 昌久
髙山, 輝彦
発行日: 1997年 9月
出版社(者): Society of Nuclear Medicine
雑誌名: Journal of Nuclear Medicine Technology
ISSN: 0091-4916
巻: 25
号: 3
開始ページ: 181
終了ページ: 186
キーワード: Electrocardiogram-gated SPECT imaging
Regional myocardial uptake
Technetium-99m-MIBI
抄録: Technetium-99m-MlBI uptake was compared between ECG-gated and ungated SPECT images in 10 normal subjects and 10 patients with coronary artery disease to investigate the effects of wall motion on regional myocardial uptake. Methods: Left ventricular ejection fraction (LVEF) and wall motion were evaluated using the first-pass data acquired immediately after injection of 1110 MBq 99mTc-MIBI. A transaxial ungated image was reconstructed with cumulative data during a cardiac cycle. For transaxial gated images, data during a cardiac cycle were divided into eight frames and the first seven frames were used. The lateral/septal ratios for ungated and gated images were obtained using the counts in the ROIs drawn in the lateral and the septal walls. Results: In 10 normal subjects, the lateral/septal ratio for gated increased during end-systole. The mean of the lateral/septal ratio was significantly lower for ungated than for gated (1.025 vs. 1.077, p < 0.05). In patients with septal wall asynergy and a normokinetic lateral wall, the mean of the lateral/septal ratios was significantly lower for ungated than for gated (1.267 vs. 1.325, p < 0.01). Conclusion: Ungated SPECT acquisition may underestimate regional myocardial uptake when myocardial wall motion is good, therefore, ECG-gated data should be acquired for accurate assessment of regional myocardial uptake of 99mTc-MIBI.
URI: http://hdl.handle.net/2297/7451
資料種別: Journal Article
版表示: publisher
出現コレクション:1. 査読済論文(医学・保健)

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