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タイトル: Systolic dysfunction and blood pressure responses to supine exercise in patients with hypertrophic cardiomyopathy
著者: Shimizu, Masami
Ino, Hidekazu
Okeie, Kazuyasu
Yamaguchi, Masato
Nagata, Mitsuru
Hayashi, Kenshi link image link image
Itoh, Hideki
Iwaki, Taku
Oe, Kotaro
Konno, Tetsuo link image
Taki, Junichi link image link image
Mabuchi, Hiroshi
清水, 賢巳
井野, 秀一
瀧, 淳一
馬渕, 宏
発行日: 2001年
出版社(者): 日本循環器学会
雑誌名: Japanese Circulation Journal
ISSN: 0047-1828
巻: 65
号: 4
開始ページ: 325
終了ページ: 329
キーワード: Blood pressure response
Hypertrophic cardiomyopathy
Systolic dysfunction
抄録: Left ventricular function and blood pressure responses were evaluated in 56 patients with non-obstructive hypertrophic cardiomyopathy (HCM) and 12 control subjects by using a radionuclide ventricular function monitor during supine ergometer exercise. Patients with HCM were divided into 2 groups: (i) group A had no decrease in ejection fraction (EF) during exercise; and (ii) group B had a decrease in EF during exercise. During exercise, the change in end-diastolic volume did not differ between the 3 groups. In contrast, the change in end-systolic volume differed between the 3 groups (p<0.0001). The change in systolic blood pressure (SBP) also differed significantly between the 3 groups. The change in SBP in group B was smaller than that in the control group and group A, and changes in the EF and changes in the SBP between rest and peak exercise showed a significant correlation (p<0.005). These results suggest that exercise-induced systolic dysfunction in patients with non-obstructive HCM may contribute to abnormal blood pressure response in those patients.
DOI: 10.1253/jcj.65.325
URI: http://hdl.handle.net/2297/7528
関連URI: http://www.jstage.jst.go.jp/article/jcj/65/4/65_325/_article/-char/en
資料種別: Journal Article
版表示: publisher
出現コレクション:1. 査読済論文(医学・保健)

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